Animesh Das, Akash Jana and Biplab Maji
Chem. Commun., 2020,56, 4284-4287
DOI:
10.1039/D0CC00575D,
Communication
A straightforward strategy was developed for the arylation and olefination at the C5-position of the N-(alkyl)pyrimidin-2-amine core with readily available aryl halides and alkenes, respectively. This approach was highly regioselective, and the transformation was achieved based on two different (Pd(II)/Pd(IV)) and (Pd(0)/Pd(II)) catalytic cycles.
