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An intramolecular glycosylation strategy was used to synthesize a series of new glycoazobenzene macrocycles with high α-selectivity and interesting chiroptical properties. The photoisomerization of an azobenzene template influences mainly the efficiency of the glycosylation.

Graphical abstract: Stereoselective synthesis and properties of glycoazobenzene macrocycles through intramolecular glycosylation

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