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Enantiopure A4L4 tetrahedral cages (either ΔΔΔΔ or ΛΛΛΛ) were obtained through the anion-coordination-driven assembly (ACDA) of phosphate anions with C3-symmetric tris-bis(urea) ligands bearing chiral groups.

Graphical abstract: Chirality transcription in the anion-coordination-driven assembly of tetrahedral cages

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