Issue 9, 2020
From the journal:

Chemical Communications

Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe†

Wei Li,a   Shulu Yin,a   Xiangyang Gong,a   Wang Xu,a   Ronghua Yang, ORCID logo b   Yichao Wan,c   Lin Yuan ORCID logo *a  and  XiaoBing Zhang ORCID logo a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, P. R. China
E-mail: lyuan@hnu.edu.cn

b School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, P. R. China

c Key Laboratory of Theoretical Organic Chemistry and Functional Molecule (MOE), College of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, Hunan, P. R. China

Abstract

Herein, a novel two-photon ratiometric fluorescence assay was proposed for monitoring endogenous steroid sulfatase (STS) activity, which could be applied for the ratiometric imaging of STS activity in the endoplasmic reticulum of living cells and tissues and also could be used to distinguish estrogen-dependent tumor cells from other types of cells.

Graphical abstract: Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe

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Article information

DOI
https://doi.org/10.1039/C9CC08672B
Article type
Communication
Submitted
06 Nov 2019
Accepted
19 Dec 2019
First published
19 Dec 2019

Chem. Commun., 2020,56, 1349-1352

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Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe

W. Li, S. Yin, X. Gong, W. Xu, R. Yang, Y. Wan, L. Yuan and X. Zhang, Chem. Commun., 2020, 56, 1349 DOI: 10.1039/C9CC08672B

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