BODIPY-based hydrazine as a fluorescent probe for sensitive and selective detection of nitric oxide: a new strategy

Abstract

A novel fluorescent probe 8-HB was developed with a BODIPY as a fluorophore and 8-substituted hydrazine as a reactive site for sensitive and selective detection of nitric oxide (NO), generating major fluorescent dehydrazinated BODIPY and minor non-fluorescent azide BODIPY. Moreover, 8-HB can achieve specific imaging of endogenous NO in living cells.