Jump to main content
Jump to site search


Rhodium-catalyzed asymmetric intramolecular hydroarylation of allenes: access to functionalized benzocycles

Author affiliations

Abstract

A rhodium-catalyzed regio- and enantioselective cyclization of tethered allenylbenzenes is reported. Employing a RhI/Josiphos catalytic system a diverse set of 6-membered, α-chiral benzocycles were obtained, scaffolds found in many bioactive compounds. Moreover, a gram scale reaction as well as the application of suitable transformations are demonstrated.

Graphical abstract: Rhodium-catalyzed asymmetric intramolecular hydroarylation of allenes: access to functionalized benzocycles

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Aug 2019, accepted on 06 Sep 2019 and first published on 10 Sep 2019


Article type: Edge Article
DOI: 10.1039/C9SC03894A
Chem. Sci., 2019, Advance Article
  • Open access: Creative Commons BY-NC license
    All publication charges for this article have been paid for by the Royal Society of Chemistry

  •   Request permissions

    Rhodium-catalyzed asymmetric intramolecular hydroarylation of allenes: access to functionalized benzocycles

    D. Berthold, J. Klett and B. Breit, Chem. Sci., 2019, Advance Article , DOI: 10.1039/C9SC03894A

    This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements