An efficient method for the synthesis of N-thiomethyl benzimidazoles from o-phenylenediamines, thiophenols, and aldehydes via C–N/C–S bond formation under metal-free conditions is described. A broad range of functional groups attached to the substrates were well tolerated in this reaction system. Stable and low-toxicity paraformaldehyde was used as the carbon source.
J. Tian, S. Yuan, F. Xiao, H. Huang and G. Deng, RSC Adv., 2019, 9, 30570 DOI: 10.1039/C9RA06144D
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