Issue 37, 2019
From the journal:

RSC Advances

Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells†

Yu Mei Que,a   Xiao Qing Fan,b   Xiao Juan Lin,a   Xiao Li Jiang,a   Ping Ping Hu, ORCID logo *a   Xiao Yong Tonga  and  Qun You Tan*b  

* Corresponding authors

a Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, PR China
E-mail: huping07@163.com

b Department of Thoracic Surgery, Institute of Surgery Research, Daping Hospital, Army Medical University, Chongqing 400042, P. R. China
E-mail: tanqy001@163.com

Abstract

The molecular mechanism of cancer cell death caused by silver nanoparticles (AgNPs) of different sizes is investigated. Compared with the larger nanoparticles, 13 nm AgNPs significantly inhibit the migration and invasiveness of lung adenocarcinoma A549 cells, induce elevated reactive oxygen species and lead to NF-κB directed cellular apoptosis.

Graphical abstract: Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C9RA03662H
Article type
Paper
Submitted
15 May 2019
Accepted
20 Jun 2019
First published
05 Jul 2019
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2019,9, 21134-21138

Permissions

Request permissions

Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells

Y. M. Que, X. Q. Fan, X. J. Lin, X. L. Jiang, P. P. Hu, X. Y. Tong and Q. Y. Tan, RSC Adv., 2019, 9, 21134 DOI: 10.1039/C9RA03662H

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements