Issue 34, 2019, Issue in Progress

Laser-treated glass platform for rapid wicking-driven transport and particle separation in bio microfluidics

Abstract

In this work, we present a laser-based fabrication technique for direct patterning of micro-channels consisting of interconnected micro-cracks on soda-lime glass. Using a CO2 laser to deposit energy at a linear rate of 18.75 to 93.75 mJ mm−1, we were able to manipulate the micro-crack formation, while enabling rapid manufacturing and scalable production of cracked-glass microfluidic patterns on glass. At the higher end of the energy deposition rate (93.75 mJ mm−1), the laser fabricated microfluidic channels (1 mm wide and 20 mm long) had extremely fast wicking speeds (24.2 mm s−1, ×10 faster than filter paper) as a result of significant capillary action and laser-induced surface hydrophilization. At the lower end (18.75 mJ mm−1), 3–4 μm wide micro-cracked crevices resulted in an increased mesh/sieve density, hence, more efficiently filtering particle-laden liquid samples. The reproducibility tests revealed an averaged wicking speed of 10.6 ± 1.5 mm s−1 measured over 21 samples fabricated under similar conditions, similar to that of filter paper (∼85%). The micro-cracked channels exhibited a stable shelf life of at least 82 days with a wicking speed within 10–13 mm s−1.

Graphical abstract: Laser-treated glass platform for rapid wicking-driven transport and particle separation in bio microfluidics

Article information

Article type
Paper
Submitted
08 May 2019
Accepted
11 Jun 2019
First published
21 Jun 2019
This article is Open Access
Creative Commons BY license

RSC Adv., 2019,9, 19531-19538

Laser-treated glass platform for rapid wicking-driven transport and particle separation in bio microfluidics

H. Jiang, M. Ochoa, R. Rahimi, W. Yu and B. Ziaie, RSC Adv., 2019, 9, 19531 DOI: 10.1039/C9RA03448J

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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