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Issue 43, 2019
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An acetylcholinesterase biosensor with high stability and sensitivity based on silver nanowire–graphene–TiO2 for the detection of organophosphate pesticides

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Abstract

An electrochemical acetylcholinesterase biosensor based on silver nanowire, graphene, TiO2 sol–gel, chitosan and acetylcholinesterase has been fabricated successfully for the detection of organophosphate pesticides. The outstanding electrical properties of silver nanowires and graphene, and moreover the self-assembly of these two nanomaterials make the biosensor highly sensitive. Simultaneously, the immobilization efficiency of the enzyme is greatly improved by the action of the TiO2 fixed matrix. Under optimum conditions, the biosensor exhibited excellent performance for the detection of dichlorvos with a linearity in the range of 0.036 μM to 22.63 μM and the detection limit was found to be 7.4 nM. The biosensor was highly reproducible and stable during detection and storage.

Graphical abstract: An acetylcholinesterase biosensor with high stability and sensitivity based on silver nanowire–graphene–TiO2 for the detection of organophosphate pesticides

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Publication details

The article was received on 20 Mar 2019, accepted on 06 Aug 2019 and first published on 13 Aug 2019


Article type: Paper
DOI: 10.1039/C9RA02140J
RSC Adv., 2019,9, 25248-25256
  • Open access: Creative Commons BY license
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    An acetylcholinesterase biosensor with high stability and sensitivity based on silver nanowire–graphene–TiO2 for the detection of organophosphate pesticides

    J. Zhang, B. Wang, Y. Li, W. Shu, H. Hu and L. Yang, RSC Adv., 2019, 9, 25248
    DOI: 10.1039/C9RA02140J

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