Issue 30, 2019, Issue in Progress

Copper-catalyzed intramolecular cross dehydrogenative coupling approach to coumestans from 2′-hydroxyl-3-arylcoumarins

Abstract

A copper-catalyzed intramolecular cross dehydrogenative C–O coupling reaction of 2′-hydroxyl-3-arylcoumarins was developed. This protocol provided a facile and efficient strategy for the construction of natural coumestans and derivatives in moderate to high yields. This transformation exhibited good functional group compatibility and was amenable to substrates with free phenolic hydroxyl groups.

Graphical abstract: Copper-catalyzed intramolecular cross dehydrogenative coupling approach to coumestans from 2′-hydroxyl-3-arylcoumarins

Supplementary files

Article information

Article type
Paper
Submitted
13 Mar 2019
Accepted
27 May 2019
First published
03 Jun 2019
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2019,9, 17391-17398

Copper-catalyzed intramolecular cross dehydrogenative coupling approach to coumestans from 2′-hydroxyl-3-arylcoumarins

X. Song, X. Luo, J. Sheng, J. Li, Z. Zhu, Z. Du, H. Miao, M. Yan, M. Li and Y. Zou, RSC Adv., 2019, 9, 17391 DOI: 10.1039/C9RA01909J

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