Modular design for fluorophore homodimer probes using diethylentriamine as a common spacer

Abstract

Cationic fluorophore homodimer probes 1 and 2 bearing 7-aminocoumarin and naphthalimide dyes, respectively, connected via diethylenetriamine (DETA) spacer, have been developed to demonstrate the validity of our modular probe design on the basis of the triamine-based spacer.