Palladium-catalyzed allylation of aminophenol with alkynes to construct C–N bonds†
Abstract
A method for the allylic alkylation of aminophenol with alkynes was developed using a palladium-catalysed allylation reaction with 100% atom economy. A series of structurally diverse N-allylic substituted allylamines were synthesized in good yields with high chemo-, regio-, and stereoselectivities under mild conditions.
- This article is part of the themed collection: Synthetic methodology in OBC