Jump to main content
Jump to site search

Issue 4, 2019
Previous Article Next Article

Base-promoted direct synthesis of functionalized N-arylindoles via the cascade reactions of allenic ketones with indoles

Author affiliations

Abstract

A convenient Cs2CO3-promoted cascade benzannulation reaction of allenic ketones with indoles was achieved for the synthesis of functionalized N-arylindole derivatives under transition-metal-free conditions. A series of readily available starting materials can undergo the process successfully. It represents a practical method for the construction of N-arylindole scaffolds with high atom economy.

Graphical abstract: Base-promoted direct synthesis of functionalized N-arylindoles via the cascade reactions of allenic ketones with indoles

Back to tab navigation

Supplementary files

Publication details

The article was received on 23 Nov 2018, accepted on 27 Dec 2018 and first published on 28 Dec 2018


Article type: Communication
DOI: 10.1039/C8OB02921K
Citation: Org. Biomol. Chem., 2019,17, 789-793
  •   Request permissions

    Base-promoted direct synthesis of functionalized N-arylindoles via the cascade reactions of allenic ketones with indoles

    S. Li, X. Wu and S. Chen, Org. Biomol. Chem., 2019, 17, 789
    DOI: 10.1039/C8OB02921K

Search articles by author

Spotlight

Advertisements