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Issue 37, 2019
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Quinacetophenone: a simple precursor for synthesis of phenoxazines

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Abstract

Quinacetophenone is a versatile and easy accessible building block for synthesis of various biologically active heterocyclic compounds. The inherent chemical reactivity of quinacetophenone has been hitherto utilized to construct various privileged organic molecules such as chalcones, chromones, flavonoids, coumarins and azoles etc. Herein we present an operationally simple method of synthesis of phenoxazines from quinacetophenone and anilines that exploits the inherent chemical reactivity of quinacetophenone. ESI-MS was used as a tool to establish the most plausible reaction mechanism.

Graphical abstract: Quinacetophenone: a simple precursor for synthesis of phenoxazines

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Supplementary files

Article information


Submitted
08 Jul 2019
Accepted
28 Aug 2019
First published
28 Aug 2019

New J. Chem., 2019,43, 14952-14960
Article type
Paper

Quinacetophenone: a simple precursor for synthesis of phenoxazines

S. N. Nunewar, B. B. Muthyala, S. Dastari and N. D. Tangellamudi, New J. Chem., 2019, 43, 14952
DOI: 10.1039/C9NJ03525G

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