An efficient multicomponent synthesis of sulfonamide–thiazolidinone hybrids has been achieved by a one-pot reaction of sulfonyl hydrazides, isothiocyanates, and dialkyl acetylene dicarboxylates under catalyst-free conditions at room temperature. The method creates two new C–N and one C–S bonds in a single operation, and is endowed with excellent regioselectivity.
Preeti and K. N. Singh, New J. Chem., 2019, 43, 6288 DOI: 10.1039/C9NJ00055K
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