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On-the-fly exchangeable microfluidic nozzles for facile production of various monodisperse micromaterials

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Abstract

Microfluidic manufacturing platforms have advanced the production of monodisperse, shape-controlled, and chemically defined micromaterials. However, conventional microfabrication platforms are typically designed and fabricated as single-purpose and single-use tools, which limits their efficiency, versatility, and overall potential. We here present an on-the-fly exchangeable nozzle concept that operates in a transparent, 3D, and reusable microfluidic device produced without cleanroom technology. The facile exchange and repositioning of the nozzles readily enables the production of monodisperse water-in-oil and oil-in-water emulsions, solid and core–shell microspheres, microfibers, and even Janus type micromaterials with controlled diameters ranging from 10 to 1000 μm using a single microfluidic device.

Graphical abstract: On-the-fly exchangeable microfluidic nozzles for facile production of various monodisperse micromaterials

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Publication details

The article was received on 16 Jan 2019, accepted on 13 Apr 2019 and first published on 16 Apr 2019


Article type: Paper
DOI: 10.1039/C9LC00054B
Lab Chip, 2019, Advance Article

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    On-the-fly exchangeable microfluidic nozzles for facile production of various monodisperse micromaterials

    T. Kamperman, B. van Loo, M. Gurian, S. Henke, M. Karperien and J. Leijten, Lab Chip, 2019, Advance Article , DOI: 10.1039/C9LC00054B

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