Development of a solvent-reagent selection guide for the formation of thioesters†
Andrew
Jordan 
*a
and
Helen F.
Sneddon
*b
*a
and
Helen F.
Sneddon
*b
Abstract
For the first time a solvent-reagent guide has been developed with a view to providing greener synthetic conditions for the preparation of thioesters. A number of solvents and reagents were evaluated and optimum conditions were applied to the synthesis of pharmaceutically relevant building block-like molecules.
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