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Issue 4, 2019
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Caffeine release and absorption from caffeinated gums

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Abstract

The objectives of this study were to estimate the impact of chewing time on caffeine release from gum and to understand caffeine pharmacokinetics. Caffeine release increased with chewing time (2 min < 5 min < 10 min). Furthermore, two plasma caffeine concentration peaks were observed suggesting that caffeine absorption occurs both through the oral mucosa and gastrointestinal tract. This is of practical relevance to maximise caffeine doses and to synchronise effort with peak caffeine concentration.

Graphical abstract: Caffeine release and absorption from caffeinated gums

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Article information


Submitted
28 Feb 2019
Accepted
19 Mar 2019
First published
22 Mar 2019

Food Funct., 2019,10, 1792-1796
Article type
Communication

Caffeine release and absorption from caffeinated gums

C. Morris, S. M. Viriot, Q. U. A. Farooq Mirza, G. A. Morris and A. Lynn, Food Funct., 2019, 10, 1792
DOI: 10.1039/C9FO00431A

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