Multifunctional Ag@MOF-5@chitosan non-woven cloth composites for sulfur mustard decontamination and hemostasis

Abstract

Attachment of MOF-5 particles on the surface of carboxymethylated non-woven chitosan cloth (denoted MOF-5@chitosan) was achieved by a layer-by-layer technique in an alternating bath of Zn(OAc)₂·2H₂O and terephthalic acid solutions. Afterwards, silver nanoparticles were formed/loaded within the resulting MOF-5@chitosan by irradiating at 350 nm wavelength the composite immersed in an aqueous solution of silver nitrate of different concentrations, leading to the formation of ternary composites (denoted Ag@MOF-5@chitosan) which were thoroughly characterized by various techniques. Decontamination of HD over the composites was systematically studied and the results showed that decontamination efficacy increased with the increase of silver amount. The decontamination rate constant and half-life of HD were found to be 0.011 min⁻¹ and 63.0 min over the optimal composite, respectively. Remarkably, attachment of the silver nanoparticles and MOF-5 on the chitosan cloth surface did not interfere with chitosan's original hemostatic capability that was confirmed through the arterial hemostasis of rats. It is expected that the multifunctional composite material can find practical applications in the fields of hemostasis, sterilization and chemical war agent decontamination.