An integrated urea and halogen bond donor based receptor for superior and selective sensing of phosphates†
A new RuII based bis-heteroleptic ditopic receptor, 1[PF6]2 (C44H33F12IN10OP2Ru), having integrated anion binding iodotriazole (halogen bond donor) and urea units (–NH bond donor) is employed for selective sensing of phosphates (e.g., H2PO4− and HP2O73−). 1[PF6]2 showed superiority in phosphate sensing in CH3CN as compared to its hydrogen bond donor analogue, 2[PF6]2 (C44H34F12N10OP2Ru), non-urea halogen bond analogue, 3[PF6]2 (C38H27F12IN8P2Ru) and non-urea hydrogen bond donor analogue, 4[PF6]2 (C38H28F12N8P2Ru) in terms of enhanced binding constant values, longer excited state lifetimes and lower detection limit values. 1H-NMR, Isothermal Titration Calorimetry (ITC) and photophysical studies revealed the implementation of the combined role of both the halogen bond donor iodotriazole unit and the –NH unit of the urea moiety for selective and enhanced binding of phosphates.
- This article is part of the themed collection: 1st International Conference on Noncovalent Interactions