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A facile strategy to realize a single/double photon excitation-dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separate irradiation channels

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Abstract

A novel difluoroboron fluorophore with an electron donor–acceptor conjugated structure was synthesized with 26.5% fluorescence quantum yield, 18 035 GM two-photon absorbing cross-section, and undetectable two-photon fluorescence, resulting in 25% 1O2 quantum yield. The unique optical behavior of CNFBBN enabled one-photon fluorescence imaging and two-photon phototherapy against HeLa cancer cells, irradiated at separate wavelengths.

Graphical abstract: A facile strategy to realize a single/double photon excitation-dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separate irradiation channels

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Publication details

The article was received on 11 Oct 2019, accepted on 02 Dec 2019 and first published on 03 Dec 2019


Article type: Communication
DOI: 10.1039/C9CC07968H
Chem. Commun., 2020, Advance Article

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    A facile strategy to realize a single/double photon excitation-dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separate irradiation channels

    L. Kong, Z. Huang, S. Zhang, J. Song, Y. Zhang, X. Bai, J. Yang and L. Li, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC07968H

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