Issue 95, 2019

A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery

Abstract

A novel bright near-infrared II (NIR-II, 1000–1700 nm) fluorescent probe with excellent water-solubility, superior photostability, and excellent in vitro and in vivo biocompatibility was facilely synthesized for in vivo biomedical imaging of xenograft breast tumor and chemically induced spontaneous breast carcinoma. To the best of our knowledge, it is the first time that the superior practical applications of this NIR-II probe in dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma imaging and image-guided rat carcinoma surgery were demonstrated.

Graphical abstract: A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
01 Oct 2019
Accepted
04 Nov 2019
First published
05 Nov 2019

Chem. Commun., 2019,55, 14287-14290

A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery

X. Zeng, L. Xie, D. Chen, S. Li, J. Nong, B. Wang, L. Tang, Q. Li, Y. Li, Z. Deng, X. Hong, M. Wu and Y. Xiao, Chem. Commun., 2019, 55, 14287 DOI: 10.1039/C9CC07694H

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