Issue 91, 2019
From the journal:

Chemical Communications

Sensitive discrimination of glycoproteins and cell differentiation with an array sensing platform exploiting pyrene-derived amphiphile/surfactant assemblies†

Xin Lin,a   Lifang Gao,a   Jianhua Wang ORCID logo a  and  Xuwei Chen ORCID logo *a  

* Corresponding authors

a Research Center for Analytical Sciences, Department of Chemistry, Northeastern University, Box 332, Shenyang 110819, China
E-mail: chenxuwei@mail.neu.edu.cn
Fax: +86 24 83687659
Tel: +86 24 83684533

Abstract

An array sensing platform exploiting phenyl boronic acid-functionalized pyrene amphiphile/surfactant assemblies is constructed for glycoprotein discrimination, achieving a discrimination sensitivity of 50 nM. Gastric cancer cell lines of various differentiation grades are successfully discriminated, demonstrating its great potential in sensitive differentiation of glycoprotein-related samples in biomedical diagnosis.

Graphical abstract: Sensitive discrimination of glycoproteins and cell differentiation with an array sensing platform exploiting pyrene-derived amphiphile/surfactant assemblies

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Article information

DOI
https://doi.org/10.1039/C9CC07515A
Article type
Communication
Submitted
25 Sep 2019
Accepted
17 Oct 2019
First published
17 Oct 2019

Chem. Commun., 2019,55, 13673-13676

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Sensitive discrimination of glycoproteins and cell differentiation with an array sensing platform exploiting pyrene-derived amphiphile/surfactant assemblies

X. Lin, L. Gao, J. Wang and X. Chen, Chem. Commun., 2019, 55, 13673 DOI: 10.1039/C9CC07515A

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