Jump to main content
Jump to site search

Issue 95, 2019
Previous Article Next Article

Cooperative enhancement of antibacterial activity of sanguinarine drug through p-sulfonatocalix[6]arene functionalized silver nanoparticles

Author affiliations

Abstract

The amelioration of antibacterial efficacy along with the reduced minimum inhibitory concentration (MIC) of sanguinarine (SGR) drug have been demonstrated through the uptake of SGR by p-sulfonatocalix[6]arene functionalized silver nanoparticles. The large upward pKa shift and enhanced stability of SGR resulting from the favorable supra-nanomolecular strategy are deciphered into an improved antibacterial drug against different pathogenic micro-organisms including multi drug resistant bacteria.

Graphical abstract: Cooperative enhancement of antibacterial activity of sanguinarine drug through p-sulfonatocalix[6]arene functionalized silver nanoparticles

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Sep 2019, accepted on 04 Nov 2019 and first published on 05 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC07378G
Chem. Commun., 2019,55, 14275-14278

  •   Request permissions

    Cooperative enhancement of antibacterial activity of sanguinarine drug through p-sulfonatocalix[6]arene functionalized silver nanoparticles

    C. Mehra, R. Gala, A. Kakatkar, V. Kumar, R. Khurana, S. Chatterjee, N. N. Kumar, N. Barooah, A. C. Bhasikuttan and J. Mohanty, Chem. Commun., 2019, 55, 14275
    DOI: 10.1039/C9CC07378G

Search articles by author

Spotlight

Advertisements