Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 74, 2019
Previous Article Next Article

Silver-catalyzed oxidative 1,2-alkyletherification of unactivated alkenes with α-bromoalkyl carbonyls: facile access to highly substituted 2,3-dihydrofurans

Author affiliations

Abstract

A new, general silver-catalyzed oxidative 1,2-alkyletherification of unactivated olefinic ketones with primary, secondary and tertiary α-bromoalkyl carbonyls promoted by tert-butyl hydroperoxide (TBHP) and Et3N has been developed. Through the cooperative action of Ag2O, TBHP and Et3N, the reaction enables the construction of highly valuable quaternary-carbon-possessing 2,3-dihydrofuran frameworks using a concomitant intramolecular annulation strategy.

Graphical abstract: Silver-catalyzed oxidative 1,2-alkyletherification of unactivated alkenes with α-bromoalkyl carbonyls: facile access to highly substituted 2,3-dihydrofurans

Back to tab navigation

Supplementary files

Article information


Submitted
23 Jul 2019
Accepted
19 Aug 2019
First published
19 Aug 2019

Chem. Commun., 2019,55, 11111-11114
Article type
Communication

Silver-catalyzed oxidative 1,2-alkyletherification of unactivated alkenes with α-bromoalkyl carbonyls: facile access to highly substituted 2,3-dihydrofurans

W. Wei, M. Luo, F. Teng, R. Song and J. Li, Chem. Commun., 2019, 55, 11111
DOI: 10.1039/C9CC05695E

Social activity

Search articles by author

Spotlight

Advertisements