Issue 76, 2019

Simple and robust polymer-based sensor for rapid cancer detection using serum

Abstract

We report a polymer-based sensor that rapidly detects cancer based on changes in serum protein levels. Using three ratiometric fluorescence outputs, this simple system identifies early stage and metastatic lung cancer with a high level of accuracy exceeding many biomarker-based assays, making it an attractive strategy for point-of-care testing.

Graphical abstract: Simple and robust polymer-based sensor for rapid cancer detection using serum

Supplementary files

Article information

Article type
Communication
Submitted
11 Jul 2019
Accepted
02 Sep 2019
First published
02 Sep 2019

Chem. Commun., 2019,55, 11458-11461

Author version available

Simple and robust polymer-based sensor for rapid cancer detection using serum

N. D. B. Le, A. K. Singla, Y. Geng, J. Han, K. Seehafer, G. Prakash, D. F. Moyano, C. M. Downey, M. J. Monument, D. Itani, U. H. F. Bunz, F. R. Jirik and V. M. Rotello, Chem. Commun., 2019, 55, 11458 DOI: 10.1039/C9CC04854E

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