Issue 65, 2019

Reductive stress imaging in the endoplasmic reticulum by using living cells and zebrafish

Abstract

Excessive accumulation of reducing agents in the ER leads to a constitutively high UPR. And the co-function of GSH, Cys and HOCl in biological processes is not well understood. To address this, a TP probe, NPCC, was developed for monitoring reductive stress in the ER. It can also distinguish cancer cells from normal cells.

Graphical abstract: Reductive stress imaging in the endoplasmic reticulum by using living cells and zebrafish

Supplementary files

Article information

Article type
Communication
Submitted
24 Jun 2019
Accepted
19 Jul 2019
First published
20 Jul 2019

Chem. Commun., 2019,55, 9629-9632

Reductive stress imaging in the endoplasmic reticulum by using living cells and zebrafish

H. Niu, Y. Zhang, F. Zhao, S. Mo, W. Cao, Y. Ye and Y. Zhao, Chem. Commun., 2019, 55, 9629 DOI: 10.1039/C9CC04711E

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