An unexpected multi-component one-pot cascade reaction to access furanobenzodihydropyran-fused polycyclic heterocycles

Abstract

An unexpected multi-component one-pot cascade reaction of hydroxyketones with ortho-hydroxychalcones has been developed to afford an array of new furanobenzopyran-fused polycyclic compounds with complex molecular architectures. This reaction not only establishes a new reaction mode of ortho-hydroxychalcones but also provides an expedient and convenient synthetic strategy to access complex furanobenzopyran-fused heterocycles.