Issue 37, 2019
From the journal:

Chemical Communications

Electrochemical fabrication of fibrin gels via cascade reaction for cell culture†

Noriko Taira,a   Kosuke Ino, ORCID logo *a   Tatsuki Kumagai,b   Yuji Nashimoto ORCID logo ac  and  Hitoshi Shiku*a  

* Corresponding authors

a Graduate School of Engineering, Tohoku University, 6-6-11 Aramaki-aza Aoba, Aoba-ku, Sendai 980-8579, Japan
E-mail: kosuke.ino@tohoku.ac.jp, hitoshi.shiku.c3@tohoku.ac.jp
Fax: +81-22-795-5872
Tel: +81-22-795-5872

b Graduate School of Environmental Studies, Tohoku University, 6-6-11 Aramaki-aza Aoba, Aoba-ku, Sendai 980-8579, Japan

c Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, 6-3 Aramaki-aza Aoba, Aoba-ku, Sendai 980-8578, Japan

Abstract

We present a new strategy for fabricating fibrin gels by electrochemically controlling a cascade reaction and its application in cell culture. In this strategy, Ca2+ is released from CaCO3 particles via electrochemical acidification. In the presence of the released Ca2+, the activated cascade reaction produces fibrin gels.

Graphical abstract: Electrochemical fabrication of fibrin gels via cascade reaction for cell culture

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Article information

DOI
https://doi.org/10.1039/C9CC01576K
Article type
Communication
Submitted
25 Feb 2019
Accepted
02 Apr 2019
First published
03 Apr 2019

Chem. Commun., 2019,55, 5335-5338

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Electrochemical fabrication of fibrin gels via cascade reaction for cell culture

N. Taira, K. Ino, T. Kumagai, Y. Nashimoto and H. Shiku, Chem. Commun., 2019, 55, 5335 DOI: 10.1039/C9CC01576K

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