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Issue 14, 2019
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A self-assembled peptide nucleic acid–microRNA nanocomplex for dual modulation of cancer-related microRNAs

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Abstract

Here, we report a new strategy for the construction of a peptide nucleic acid–microRNA nanocomplex with dual function to simultaneously suppress oncogenic microRNAs and upregulate tumor-suppressive microRNAs in target cancer cells.

Graphical abstract: A self-assembled peptide nucleic acid–microRNA nanocomplex for dual modulation of cancer-related microRNAs

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Supplementary files

Article information


Submitted
01 Jan 2019
Accepted
22 Jan 2019
First published
23 Jan 2019

Chem. Commun., 2019,55, 2106-2109
Article type
Communication

A self-assembled peptide nucleic acid–microRNA nanocomplex for dual modulation of cancer-related microRNAs

X. Wang, X. Xiao, B. Zhang, J. Li and Y. Zhang, Chem. Commun., 2019, 55, 2106
DOI: 10.1039/C9CC00002J

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