A sensitive photoelectrochemical assay of miRNA-155 based on a CdSe QDs//NPC-ZnO polyhedra photocurrent-direction switching system and target-triggered strand displacement amplification strategy

Leixia Meng; Yanmei Li; Ruiying Yang; Xiaohua Zhang; Cuicui Du; Jinhua Chen

doi:10.1039/C8CC09411J

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A sensitive photoelectrochemical assay of miRNA-155 based on a CdSe QDs//NPC-ZnO polyhedra photocurrent-direction switching system and target-triggered strand displacement amplification strategy†

Leixia Meng,^a Yanmei Li,^a Ruiying Yang,^a Xiaohua Zhang,

*^a Cuicui Du^a and Jinhua Chen

*^a

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* Corresponding authors

^a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China
E-mail: chenjinhua@hnu.edu.cn, mickyxie@hnu.edu.cn
Fax: +86-731-88821848
Tel: +86-731-88821848

Abstract

Herein, a new photoelectrochemical (PEC) biosensor based on a photocurrent direction switching system and target-triggered strand displacement amplification strategy was developed for the sensitive detection of microRNA (miRNA)-155, and it showed excellent selectivity and a low detection limit of about 49 aM.

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Article information

DOI: https://doi.org/10.1039/C8CC09411J
Article type: Communication
Submitted: 27 Nov 2018
Accepted: 17 Jan 2019
First published: 18 Jan 2019

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Chem. Commun., 2019,55, 2182-2185

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A sensitive photoelectrochemical assay of miRNA-155 based on a CdSe QDs//NPC-ZnO polyhedra photocurrent-direction switching system and target-triggered strand displacement amplification strategy

L. Meng, Y. Li, R. Yang, X. Zhang, C. Du and J. Chen, Chem. Commun., 2019, 55, 2182 DOI: 10.1039/C8CC09411J

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Chemical Communications

A sensitive photoelectrochemical assay of miRNA-155 based on a CdSe QDs//NPC-ZnO polyhedra photocurrent-direction switching system and target-triggered strand displacement amplification strategy†

Abstract

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A sensitive photoelectrochemical assay of miRNA-155 based on a CdSe QDs//NPC-ZnO polyhedra photocurrent-direction switching system and target-triggered strand displacement amplification strategy

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