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An in situ assembly strategy for the construction of a sensitive and reusable electrochemical aptasensor

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Abstract

The 5′-end thiolated aptamer is attached on the electrode surface through hybridization with immobilized assistant strands. Then the signal enhancing platform of gold nanoparticles and an electroactive Cu2+L-cysteine tag are in situ tethered on the 5′-end of the aptamer, through which, a sensitive and reusable aptasensor is facilely constructed.

Graphical abstract: An in situ assembly strategy for the construction of a sensitive and reusable electrochemical aptasensor

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Publication details

The article was received on 28 Oct 2018, accepted on 28 Nov 2018 and first published on 29 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08615J
Citation: Chem. Commun., 2019, Advance Article
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    An in situ assembly strategy for the construction of a sensitive and reusable electrochemical aptasensor

    J. Song, S. Li, F. Gao, Q. Wang and Z. Lin, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C8CC08615J

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