Jump to main content
Jump to site search


Alkenylation of unactivated alkyl bromides through visible light photocatalysis

Author affiliations

Abstract

Two visible-light driven alkenylation reactions of unactivated alkyl bromides, which were enabled by the use of Ir(dF(CF3)ppy)2(dtbbpy)PF6 as the photocatalyst and (TMS)3SiH as the atom transfer reagent to activate the alkyl bromides, were described for the first time. These protocols can be used to produce a variety of alkenes from easily available feedstock with good reaction efficiency and high chemoselectivity under mild reaction conditions. To further demonstrate the applicability of the present strategy, the alkenylation of bioactive molecules and glycosyl bromides, as well as the alkynylation of unactivated alkyl bromides, was proven to be feasible.

Graphical abstract: Alkenylation of unactivated alkyl bromides through visible light photocatalysis

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Oct 2018, accepted on 23 Nov 2018 and first published on 26 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08362B
Citation: Chem. Commun., 2019, Advance Article
  •   Request permissions

    Alkenylation of unactivated alkyl bromides through visible light photocatalysis

    Q. Zhou, S. J. S. Düsel, L. Lu, B. König and W. Xiao, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C8CC08362B

Search articles by author

Spotlight

Advertisements