Ashique Hussain Jatoi, Govind Goroba Pawar, Frédéric Robert and Yannick Landais
Chem. Commun., 2019,55, 466-469
DOI:
10.1039/C8CC08326F,
Communication
The generation of carbamoyl radicals, followed by their addition to heteroarenes, was performed under mild conditions through a metal-free photocatalyzed decarboxylation of oxamic acids. The process has been applied to the carbamoylation of heteroaromatic bases using α-aminoacid-derived oxamic acids, leading to the corresponding amides without racemization.
