Issue 12, 2019

Photoenzymatic epoxidation of styrenes


Two-component-diffusible-flavomonooxygenases are versatile biocatalysts for selective epoxidation-, hydroxylation- or halogenation reactions. Their complicated molecular architecture can be simplified using photochemical regeneration of the catalytically active, reduced FADH2 prosthetic group. In this contribution we provide the proof-of-concept and characterization for the direct regeneration of the styrene monooxygenase from Pseudomonas.

Graphical abstract: Photoenzymatic epoxidation of styrenes

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Article information

Article type
11 Oct 2018
18 Dec 2018
First published
22 Jan 2019
This article is Open Access
Creative Commons BY license

Chem. Commun., 2019,55, 1790-1792

Photoenzymatic epoxidation of styrenes

M. M. C. H. van Schie, C. E. Paul, I. W. C. E. Arends and F. Hollmann, Chem. Commun., 2019, 55, 1790 DOI: 10.1039/C8CC08149B

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