Issue 18, 2019

Application of molecularly imprinted polymer nanoparticles for degradation of the bacterial autoinducer N-hexanoyl homoserine lactone

Abstract

A novel bacterial quorum quenching system is presented. For the first time the degradation of N-L-hexanoyl homoserine lactone (C6-AHL), a Gram-negative quorum sensing autoinducer, has been enhanced using molecularly imprinted nanoparticles (MIP NPs) which were prepared using transition state analogue of the γ-lactone ring hydrolysis as template.

Graphical abstract: Application of molecularly imprinted polymer nanoparticles for degradation of the bacterial autoinducer N-hexanoyl homoserine lactone

Supplementary files

Article information

Article type
Communication
Submitted
24 Sep 2018
Accepted
04 Feb 2019
First published
04 Feb 2019

Chem. Commun., 2019,55, 2664-2667

Application of molecularly imprinted polymer nanoparticles for degradation of the bacterial autoinducer N-hexanoyl homoserine lactone

J. Garcia Lopez, E. V. Piletska, M. J. Whitcombe, J. Czulak and S. A. Piletsky, Chem. Commun., 2019, 55, 2664 DOI: 10.1039/C8CC07685E

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