Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 3, 2019
Previous Article Next Article

A stereoselective sequential organocascade and multicomponent approach for the preparation of tetrahydropyridines and chimeric derivatives

Author affiliations

Abstract

A stereoselective multicomponent approach leading to a novel class of pentasubstituted tetrahydropyridines is described. Variation of the components enabled the incorporation of peptide, sugar and steroid moieties to access chimeric derivatives. DFT calculations provide insights about the unprecedented high diastereoselectivity of the MCR.

Graphical abstract: A stereoselective sequential organocascade and multicomponent approach for the preparation of tetrahydropyridines and chimeric derivatives

Back to tab navigation

Supplementary files

Article information


Submitted
24 Aug 2018
Accepted
30 Oct 2018
First published
30 Oct 2018

Chem. Commun., 2019,55, 286-289
Article type
Communication

A stereoselective sequential organocascade and multicomponent approach for the preparation of tetrahydropyridines and chimeric derivatives

R. Echemendía, G. P. da Silva, M. Y. Kawamura, A. F. de la Torre, A. G. Corrêa, M. A. B. Ferreira, D. G. Rivera and M. W. Paixão, Chem. Commun., 2019, 55, 286
DOI: 10.1039/C8CC06871B

Social activity

Search articles by author

Spotlight

Advertisements