Issue 2, 2019

Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria

Abstract

A probe Mito-BT was constructed and synthesized by combining triphenylamine and hemicyanine, and can be used for specific ratiometric sensing of H2S. It has a rapid response time of 10 s and preferentially targets to mitochondria. Then the visualization of the change of the mitochondrial H2S concentration upon NaHS incubation by using Mito-BT staining is promising for the practical exploration of H2S-related processes in mitochondria.

Graphical abstract: Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria

Supplementary files

Article information

Article type
Paper
Submitted
27 Nov 2018
Accepted
06 Dec 2018
First published
07 Dec 2018

Anal. Methods, 2019,11, 232-235

Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria

N. Jiang, B. Wang, T. Liu, Q. Liu, Q. Wei, Y. Xing and G. Zheng, Anal. Methods, 2019, 11, 232 DOI: 10.1039/C8AY02586J

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