Issue 1, 2019
From the journal:

Analyst

A hybridization-triggered DNAzyme cascade assay for enzyme-free amplified fluorescence detection of nucleic acids†

Huizhen Wang,a   Dinggeng He,*a   Ri Wu,a   Hong Cheng,a   Wenjie Ma,a   Jin Huang,a   Hongchang Bu,a   Xiaoxiao He*a  and  Kemin Wang ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, College of Chemistry and Chemical Engineering, Hunan University, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Changsha 410082, China
E-mail: hedinggeng@hnu.edu.cn, xiaoxiaohe@hnu.edu.cn, kmwang@hnu.edu.cn

Abstract

An enzyme-free and ultrasensitive fluorescence assay for the detection of nucleic acids was successfully established by a hybridization-triggered DNAzyme cascade (HTDC). This simple and cost-effective sensor has good sensitivity, selectivity and the capability for detection of target DNA from complex fluids.

Graphical abstract: A hybridization-triggered DNAzyme cascade assay for enzyme-free amplified fluorescence detection of nucleic acids

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Article information

DOI
https://doi.org/10.1039/C8AN01796D
Article type
Communication
Submitted
17 Sep 2018
Accepted
22 Oct 2018
First published
27 Oct 2018

Analyst, 2019,144, 143-147

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A hybridization-triggered DNAzyme cascade assay for enzyme-free amplified fluorescence detection of nucleic acids

H. Wang, D. He, R. Wu, H. Cheng, W. Ma, J. Huang, H. Bu, X. He and K. Wang, Analyst, 2019, 144, 143 DOI: 10.1039/C8AN01796D

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