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Issue 37, 2018
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Fabrication of micron-sized BSA-imprinted polymers with outstanding adsorption capacity based on poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres

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Abstract

Monodisperse poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres have been fabricated by seed polymerization. From the SEM images, it is known that the obtained PGMA/PS microspheres have three different morphologies: raspberry-shaped, golf-shaped and porous structures. Based on the successful fabrication of these micropheres, bovine serum albumin (BSA)-imprinted PGMA/PS microspheres were fabricated via dopamine auto-polymerization in alkaline solution. Because dopamine does not affect the validity of the protein structure, the imprinted cavity structure on the surface of the MIPs can match the template protein molecules completely. The obtained micron-sized BSA-imprinted PGMA/PS microspheres have an excellent saturation adsorption capacity (Q = 72.7 mg gāˆ’1) and good selective adsorption for BSA (IF = 4.6).

Graphical abstract: Fabrication of micron-sized BSA-imprinted polymers with outstanding adsorption capacity based on poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres

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Publication details

The article was received on 31 May 2018, accepted on 21 Aug 2018 and first published on 23 Aug 2018


Article type: Paper
DOI: 10.1039/C8TB01423J
Citation: J. Mater. Chem. B, 2018,6, 5860-5866

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    Fabrication of micron-sized BSA-imprinted polymers with outstanding adsorption capacity based on poly(glycidyl methacrylate)/polystyrene (PGMA/PS) anisotropic microspheres

    Y. Wang, J. Zhou, C. Wu, L. Tian, B. Zhang and Q. Zhang, J. Mater. Chem. B, 2018, 6, 5860
    DOI: 10.1039/C8TB01423J

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