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Issue 41, 2018
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Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes

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Abstract

Iodine-promoted three-component synthesis of substituted β-amino sulfides has been developed starting from a propargyl ester, aliphatic secondary amine, and disulfide. This protocol provides a step-economic and highly regioselective entry to trisubstituted olefins with good substrate scope and functional group tolerance.

Graphical abstract: Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes

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Supplementary files

Article information


Submitted
23 May 2018
Accepted
19 Jun 2018
First published
27 Jun 2018

This article is Open Access

RSC Adv., 2018,8, 23319-23322
Article type
Paper

Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes

F. Xiao, D. Wang, S. Yuan, H. Huang and G. Deng, RSC Adv., 2018, 8, 23319
DOI: 10.1039/C8RA04374D

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