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Issue 26, 2018, Issue in Progress
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One-pot, sequential four-component synthesis of novel heterocyclic [3.3.3] propellane derivatives at room temperature

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Abstract

An efficient, one-pot, two-step, four-component reaction for the synthesis of propellane derivatives is described by the condensation reaction between acenaphthenequinone, malono derivatives, primary amines and β-ketoester or β-diketone derivatives in the presence of triethylamine in ethanol at room temperature. Using this procedure, all the products were obtained in good to excellent yields.

Graphical abstract: One-pot, sequential four-component synthesis of novel heterocyclic [3.3.3] propellane derivatives at room temperature

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Article information


Submitted
24 Feb 2018
Accepted
09 Apr 2018
First published
17 Apr 2018

This article is Open Access

RSC Adv., 2018,8, 14171-14176
Article type
Paper

One-pot, sequential four-component synthesis of novel heterocyclic [3.3.3] propellane derivatives at room temperature

M. Beyrati and A. Hasaninejad, RSC Adv., 2018, 8, 14171
DOI: 10.1039/C8RA01648H

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