Issue 13, 2018
From the journal:

Organic Chemistry Frontiers

A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas†

Hugo Santalla,a   Fátima Garrido,a   Generosa Gómez*a  and  Yagamare Fall ORCID logo *a  

* Corresponding authors

a Departamento de Química Orgánica, Facultad de Química and Instituto de Investigación Sanitaria Galicia Sur (IISGS), University of Vigo, Campus Marcosende, 36310 Vigo, Spain
E-mail: ggomez@uvigo.es, yagamare@uvigo.es

Abstract

After a serendipitous synthesis of a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas, a more reliable synthetic method is now described using our building blocks containing stereodefined stereochemistry at C-20.

Graphical abstract: A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8QO00338F
Article type
Research Article
Submitted
03 Apr 2018
Accepted
09 May 2018
First published
11 May 2018

Org. Chem. Front., 2018,5, 2016-2019

Permissions

Request permissions

A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

H. Santalla, F. Garrido, G. Gómez and Y. Fall, Org. Chem. Front., 2018, 5, 2016 DOI: 10.1039/C8QO00338F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements