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Issue 12, 2018
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Melanoma – role of the environment and genetics

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Melanoma rates have increased in populations that are mainly European. The main etiologic factor is ultraviolet radiation, from the sun as well as artificial tanning devices. Host factors such as skin color, number of nevi, hair and eye color and tanning ability are critical factors in modifying an individual's response to the sun. Genetic factors interact with host factors and environmental factors to increase risk. This review summarizes our current knowledge of environment and genetics on melanoma risk and on gene–environment interaction.

Graphical abstract: Melanoma – role of the environment and genetics

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The article was received on 07 Nov 2017, accepted on 07 Aug 2018 and first published on 08 Aug 2018

Article type: Perspective
DOI: 10.1039/C7PP00411G
Photochem. Photobiol. Sci., 2018,17, 1853-1860

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    Melanoma – role of the environment and genetics

    A. E. Cust, K. Mishra and M. Berwick, Photochem. Photobiol. Sci., 2018, 17, 1853
    DOI: 10.1039/C7PP00411G

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