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Issue 12, 2018

Melanoma – role of the environment and genetics

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Abstract

Melanoma rates have increased in populations that are mainly European. The main etiologic factor is ultraviolet radiation, from the sun as well as artificial tanning devices. Host factors such as skin color, number of nevi, hair and eye color and tanning ability are critical factors in modifying an individual's response to the sun. Genetic factors interact with host factors and environmental factors to increase risk. This review summarizes our current knowledge of environment and genetics on melanoma risk and on gene–environment interaction.

Graphical abstract: Melanoma – role of the environment and genetics

Article information


Submitted
07 Nov 2017
Accepted
07 Aug 2018
First published
08 Aug 2018

Photochem. Photobiol. Sci., 2018,17, 1853-1860
Article type
Perspective

Melanoma – role of the environment and genetics

A. E. Cust, K. Mishra and M. Berwick, Photochem. Photobiol. Sci., 2018, 17, 1853 DOI: 10.1039/C7PP00411G

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