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Issue 47, 2018
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B(C6F5)3-catalyzed Markovnikov addition of indoles to aryl alkynes: an approach toward bis(indolyl)alkanes

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Abstract

The first example of the metal- and solvent-free B(C6F5)3-catalyzed Markovnikov addition of indoles to aryl alkynes was disclosed. Both N–H and N-protected indoles were tolerated, leading to a wide spectrum of versatile bis(indolyl)alkanes in moderate to good yields with high regioselectivities.

Graphical abstract: B(C6F5)3-catalyzed Markovnikov addition of indoles to aryl alkynes: an approach toward bis(indolyl)alkanes

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Publication details

The article was received on 10 Nov 2018, accepted on 20 Nov 2018 and first published on 21 Nov 2018


Article type: Paper
DOI: 10.1039/C8OB02805B
Citation: Org. Biomol. Chem., 2018,16, 9274-9278
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    B(C6F5)3-catalyzed Markovnikov addition of indoles to aryl alkynes: an approach toward bis(indolyl)alkanes

    F. Ling, L. Xiao, L. Fang, C. Feng, Z. Xie, Y. Lv and W. Zhong, Org. Biomol. Chem., 2018, 16, 9274
    DOI: 10.1039/C8OB02805B

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