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Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

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Abstract

Fluoroalkylated alkynes, which are versatile building blocks for the synthesis of various biologically active organofluorine compounds, were synthesized from easily available alkynyl halides and fluoroalkyl halides by visible-light photocatalysis. Addition of fluoroalkyl radicals to alkynes and subsequent dehalogenation selectively yielded fluoroalkylated alkynes.

Graphical abstract: Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

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Publication details

The article was received on 06 Oct 2018, accepted on 06 Nov 2018 and first published on 07 Nov 2018


Article type: Communication
DOI: 10.1039/C8OB02486C
Citation: Org. Biomol. Chem., 2018, Advance Article
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    Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

    N. Iqbal, N. Iqbal, S. S. Han and E. J. Cho, Org. Biomol. Chem., 2018, Advance Article , DOI: 10.1039/C8OB02486C

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