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Issue 43, 2018
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Direct synthesis of indenes via a rhodium-catalyzed multicomponent Csp2–H annulation reaction

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Abstract

A highly efficient, direct and multicomponent route for the synthesis of indenes is reported herein. This process is catalyzed by a rhodium(III) complex and conducted under very mild conditions, making the overall process atom and step-economical. DFT mechanistic studies were performed to explore the mechanism of this reaction system.

Graphical abstract: Direct synthesis of indenes via a rhodium-catalyzed multicomponent Csp2–H annulation reaction

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Publication details

The article was received on 21 Sep 2018, accepted on 15 Oct 2018 and first published on 15 Oct 2018


Article type: Communication
DOI: 10.1039/C8OB02359J
Citation: Org. Biomol. Chem., 2018,16, 8042-8047
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    Direct synthesis of indenes via a rhodium-catalyzed multicomponent Csp2–H annulation reaction

    P. Querard and C. Li, Org. Biomol. Chem., 2018, 16, 8042
    DOI: 10.1039/C8OB02359J

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