Jump to main content
Jump to site search


Multicomponent Reactions: A Sustainable Tool to 1,2- and 1,3-Azoles

Abstract

Multicomponent Reactions (MCRs) have emerged as an efficient and eco-safe approach in organic synthesis. The influential nature of this approach has been well established in the fields of drug discovery, catalysis, material science, pharmaceutical and combinatorial chemistry. Not surprisingly, the development of multicomponent reactions leading to 1,2/1,3-azoles has expanded rapidly over the last few years. Despite their myriad synthetic applications, there is yet no exclusive review on the MCRs concerning the synthesis of 1,2/1,3-azoles. Therefore, this critical review covers the journey of MCRs to 1,2/1,3-azoles, including the reaction conditions, scope, and rationale behind the choice of catalyst as well as the proposed mechanism.

Back to tab navigation

Publication details

The article was received on 02 Aug 2018, accepted on 09 Nov 2018 and first published on 10 Nov 2018


Article type: Review Article
DOI: 10.1039/C8OB01872C
Citation: Org. Biomol. Chem., 2018, Accepted Manuscript
  •   Request permissions

    Multicomponent Reactions: A Sustainable Tool to 1,2- and 1,3-Azoles

    P. Wadhwa and K. N. Singh, Org. Biomol. Chem., 2018, Accepted Manuscript , DOI: 10.1039/C8OB01872C

Search articles by author

Spotlight

Advertisements