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Issue 33, 2018
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Metal-free oxidative radical cascade addition/oxobutylation of unactivated alkenes with acetone towards 3-(3-oxobutyl)indolines

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Abstract

A direct oxobutylation of N-allyl anilines with acetone was developed under metal-free and acid-free conditions. This reaction tolerates a series of functional groups to provide 3-(3-oxobutyl) functionalized indolines in moderate to good yields.

Graphical abstract: Metal-free oxidative radical cascade addition/oxobutylation of unactivated alkenes with acetone towards 3-(3-oxobutyl)indolines

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Publication details

The article was received on 06 Jun 2018, accepted on 02 Aug 2018 and first published on 03 Aug 2018


Article type: Paper
DOI: 10.1039/C8OB01329B
Citation: Org. Biomol. Chem., 2018,16, 6035-6038
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    Metal-free oxidative radical cascade addition/oxobutylation of unactivated alkenes with acetone towards 3-(3-oxobutyl)indolines

    C. Pan, Z. Yang, D. Gao and J. Yu, Org. Biomol. Chem., 2018, 16, 6035
    DOI: 10.1039/C8OB01329B

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